ppt-page
Heterogeneity of Antibiotics
n
nOffers more mixing than cycling
vReduce the overall selective pressure
nShould be considered rather than cycling
資料來源:
Bonhoeffer S, et al. PNAC USA.1997;94:12106-12111.
Bonten MJM, et al. CID.2001;33:1739-1746.
Fridkin SK. CID. 2003;36:1438-1444.
Bergstrom CT, et al. PNAS USA.2004;101:13285-13290.
Sandiumenge A, et al. JAC.2006;57:1197-1204
Kollef MH, et al. CID. 2006;43:S82-8.