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 <div v:shape="Rectangle_x0020_2" class=CT style='text-align:center'><span
 style='position:absolute;top:11.08%;left:10.83%;width:83.21%;height:8.43%'><span
 lang=EN-US style='font-size:91%;mso-fareast-language:ZH-TW'>Impact of
 Catheter-related </span></span><span style='position:absolute;top:20.0%;
 left:7.22%;width:90.25%;height:8.43%'><span lang=EN-US style='font-size:91%;
 mso-fareast-language:ZH-TW'>Bloodstream Infection (CRBSI)</span></span></div>
 <div v:shape="Rectangle_x0020_12">
 <div class=CB1 style='mso-margin-left-alt:468'></div>
 <div class=CB2 style='mso-margin-left-alt:720'></div>
 <div class=CB3 style='mso-margin-left-alt:1008'></div>
 <div class=CB4 style='mso-margin-left-alt:1296'></div>
 <div class=CB style='text-align:left;mso-line-spacing:"90 20 0";position:absolute;
 top:29.63%;left:11.73%;width:87.54%;height:6.02%'><span lang=EN-US
 style='font-family:"Times New Roman";mso-ascii-font-family:"Times New Roman";
 mso-fareast-font-family:新細明體;font-size:88%;mso-fareast-language:ZH-TW'>In
 US:&#13;</span></div>
 <div class=CB style='text-align:left;mso-line-spacing:"90 20 0";position:absolute;
 top:36.38%;left:11.73%;width:87.54%;height:6.02%'><span style='position:absolute;
 top:0%;left:3.09%;width:96.9%;height:100.0%'><span style='font-size:88%;
 font-weight:normal'><span style='mso-special-format:bullet;color:#006600;
 position:absolute;left:-3.19%;top:-.3em;font-family:Wingdings;font-size:150%'>§</span></span><span
 lang=EN-US style='font-family:"Times New Roman";mso-ascii-font-family:"Times New Roman";
 mso-fareast-font-family:新細明體;font-size:88%;mso-fareast-language:ZH-TW'>CRBSI:
 350,000 patients per year&#13;</span></span></div>
 <div class=CB style='text-align:left;mso-line-spacing:"90 20 0";position:absolute;
 top:43.37%;left:11.73%;width:87.54%;height:6.02%'><span style='position:absolute;
 top:0%;left:3.09%;width:96.9%;height:100.0%'><span style='font-size:88%;
 font-weight:normal'><span style='mso-special-format:bullet;color:#006600;
 position:absolute;left:-3.19%;top:-.3em;font-family:Wingdings;font-size:150%'>§</span></span><span
 lang=EN-US style='font-family:"Times New Roman";mso-ascii-font-family:"Times New Roman";
 mso-fareast-font-family:新細明體;font-size:88%;mso-fareast-language:ZH-TW'>Mortality
 rate: 12% to 25%&#13;</span></span></div>
 <div class=CB style='text-align:left;mso-line-spacing:"90 20 0";position:absolute;
 top:50.12%;left:11.73%;width:91.51%;height:6.02%'><span style='position:absolute;
 top:0%;left:2.95%;width:97.04%;height:100.0%'><span style='font-size:88%;
 font-weight:normal'><span style='mso-special-format:bullet;color:#006600;
 position:absolute;left:-3.04%;top:-.3em;font-family:Wingdings;font-size:150%'>§</span></span><span
 lang=EN-US style='font-family:"Times New Roman";mso-ascii-font-family:"Times New Roman";
 mso-fareast-font-family:新細明體;font-size:88%;mso-fareast-language:ZH-TW'>Extra-hospital
 stay : 5 to 20 days per CRBSI&#13;</span></span></div>
 <div class=CB style='text-align:left;mso-line-spacing:"90 20 0";position:absolute;
 top:57.1%;left:11.73%;width:87.54%;height:6.02%'><span style='position:absolute;
 top:0%;left:3.09%;width:96.9%;height:100.0%'><span style='font-size:88%;
 font-weight:normal'><span style='mso-special-format:bullet;color:#006600;
 position:absolute;left:-3.19%;top:-.3em;font-family:Wingdings;font-size:150%'>§</span></span><span
 lang=EN-US style='font-family:"Times New Roman";mso-ascii-font-family:"Times New Roman";
 mso-fareast-font-family:新細明體;font-size:88%;mso-fareast-language:ZH-TW'>Extra-costs
 : $34,000- $56,000<span style='mso-spacerun:yes'>  </span>per CRBSI&#13;</span></span></div>
 <div class=CB style='text-align:left;mso-line-spacing:"90 20 0";position:absolute;
 top:63.85%;left:11.73%;width:87.54%;height:6.02%'><span style='position:absolute;
 top:0%;left:3.09%;width:96.9%;height:100.0%'><span style='font-size:88%;
 font-weight:normal'><span style='mso-special-format:bullet;color:#006600;
 position:absolute;left:-3.19%;top:-.3em;font-family:Wingdings;font-size:150%'>§</span></span><span
 lang=EN-US style='font-family:"Times New Roman";mso-ascii-font-family:"Times New Roman";
 mso-fareast-font-family:新細明體;font-size:88%;mso-fareast-language:ZH-TW'>Annual
 costs: $2.3 billion&#13;</span></span></div>
 <div class=CB style='text-align:left;mso-line-spacing:"90 20 0";position:absolute;
 top:70.36%;left:11.73%;width:87.54%;height:3.61%'><span lang=EN-US
 style='font-family:"Times New Roman";mso-ascii-font-family:"Times New Roman";
 mso-fareast-font-family:新細明體;font-size:53%;mso-fareast-language:ZH-TW'><span
 style='mso-spacerun:yes'>                               </span>Stone PW, et
 al. </span><span lang=EN-US style='font-family:"Times New Roman";mso-ascii-font-family:
 "Times New Roman";mso-fareast-font-family:新細明體;font-size:53%;mso-fareast-language:
 ZH-TW'><b><i>Am J Infect Control. </i></b></span><span lang=EN-US
 style='font-family:"Times New Roman";mso-ascii-font-family:"Times New Roman";
 mso-fareast-font-family:新細明體;font-size:53%;mso-fareast-language:ZH-TW'>2005;33:542-547.&#13;</span></div>
 <div class=CB style='text-align:left;mso-line-spacing:"90 20 0";position:absolute;
 top:74.69%;left:11.73%;width:90.07%;height:4.81%'><span lang=EN-US
 style='font-family:"Times New Roman";mso-ascii-font-family:"Times New Roman";
 mso-fareast-font-family:新細明體;font-size:53%;mso-fareast-language:ZH-TW'><span
 style='mso-spacerun:yes'>      </span>Perencevich EN, et al. </span><span
 lang=EN-US style='font-family:"Times New Roman";mso-ascii-font-family:"Times New Roman";
 mso-fareast-font-family:新細明體;font-size:53%;mso-fareast-language:ZH-TW'><b><i>Infect
 Control Hosp Epidemiol </i></b></span><span lang=EN-US style='font-family:
 "Times New Roman";mso-ascii-font-family:"Times New Roman";mso-fareast-font-family:
 新細明體;font-size:53%;mso-fareast-language:ZH-TW'>2007; 28:1121-33</span><span
 lang=EN-US style='font-family:"Times New Roman";mso-ascii-font-family:"Times New Roman";
 mso-fareast-font-family:新細明體;font-size:72%;mso-fareast-language:ZH-TW'>.&#13;</span></div>
 <div class=CB style='text-align:left;mso-line-spacing:"90 20 0";position:absolute;
 top:80.24%;left:11.73%;width:87.54%;height:4.81%'><span style='position:absolute;
 top:0%;left:2.47%;width:97.31%;height:100.0%'><span style='font-size:72%;
 font-weight:normal'><span style='mso-special-format:bullet;color:#006600;
 position:absolute;left:-2.54%;top:-.3em;font-family:Wingdings;font-size:150%'>§</span></span><span
 lang=EN-US style='font-family:"Times New Roman";mso-ascii-font-family:"Times New Roman";
 mso-fareast-font-family:新細明體;font-size:72%;mso-fareast-language:ZH-TW'>More
 than 50% of CRBSI may be preventable.&#13;</span></span></div>
 <div class=CB style='text-align:left;mso-line-spacing:"90 20 0";position:absolute;
 top:85.78%;left:11.73%;width:87.54%;height:3.61%'><span lang=EN-US
 style='font-family:"Times New Roman";mso-ascii-font-family:"Times New Roman";
 mso-fareast-font-family:新細明體;font-size:53%;mso-fareast-language:ZH-TW'><span
 style='mso-spacerun:yes'>                            </span>Harbarth S, et
 al.<span style='mso-spacerun:yes'>  </span></span><span lang=EN-US
 style='font-family:"Times New Roman";mso-ascii-font-family:"Times New Roman";
 mso-fareast-font-family:新細明體;font-size:53%;mso-fareast-language:ZH-TW'><b><i>J
 Hosp Infect. </i></b></span><span lang=EN-US style='font-family:"Times New Roman";
 mso-ascii-font-family:"Times New Roman";mso-fareast-font-family:新細明體;
 font-size:53%;mso-fareast-language:ZH-TW'>2003;54:258-266.</span></div>
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