During Week 21 (May 21th to 27th), 2017, no new severe case of enterovirus infection was confirmed (Figure 1). A total of two enterovirus infection cases with severe complications (EVSC) has been confirmed by Taiwan CDC in 2017. One case was a boy aged below one year and another was a five year old boy (Table 1). These two cases were caused by Coxsackie A2 and Coxsackie A6, respectively. Figure 2 shows the geographical distribution of these cases according to their residence.