Investigation of an Infant Botulism Case, Taiwan, 2024

DOI: 10.6524/EB.2026010_42(19).0001

Yang Li^1*, Shih-Yin Tai¹, Chia-Ying Yen¹, Leng Lin², Fang-Tzu Chang¹, Ji-Jia Huang¹, Kun-Bin Wu¹

2026 Vol.42 NO.19

Correspondence Author： Yang Li^1*

Abstract：

        In January 2025, the Taiwan Centers for Disease Control was notified of a suspected infant botulism case in a 7-month-old female. The patient presented with constipation, poor appetite, and decreased activity since late December 2024. The diagnosis was confirmed by detection of the botulinum toxin gene in stool samples. Infant botulism is extremely rare in Taiwan; this is only the third confirmed case since 2015.
        Infants aged less than one year can acquire botulism by accidentally ingesting Clostridium botulinum spores from contaminated food or environmental dust. Initial symptoms typically include constipation, progressing to bilateral ptosis, limb weakness, and diminished deep tendon reflexes. To prevent the disease, we recommended enhancing parental education on hand hygiene. Parents should seek immediate medical attention if infants exhibit constipation, eyelid drooping, or limb weakness. Clinicians are advised to rapidly collect and test specimens for early diagnosis and timely administration of antitoxin.