Investigation on the Laboratory Infection of Bacillary Dysentery of a Hospital, Tainan, 2020

DOI: 10.6525/TEB.202310_39(20).0001

Yi-Hsuan Chen^*, Pei-Yi Lin, Huai-Te Tsai, Cheng-Sheng Lin, Yeuan-Perng Tsay, Tzu-Jaun Chen, Tsuey-Fong Li

2023 Vol.39 NO.20

Correspondence Author： Yi-Hsuan Chen^*

Abstract：

        On December 10, 2020, a hospital in Tainan reported a 30-year-old female infected with bacillary dysentery. The stool culture test was confirmed as Shigella flexneri 2a (sub-group B). The confirmed case was a medical technologist of the bacterial laboratory in the hospital. The test results of fecal specimens from 23 contacts were all negative. During her incubation period, the laboratory identified another case of bacillary dysentery infected with Shigella flexneri 2a. Both isolates shared the same DNA fingerprint pattern (code: SFN09.0219) by pulse-field gel electrophoresis (PFGE).
    According to the surveillance data of the Taiwan Centers for Disease Control (TCDC), the prevalent type of S. flexneri 2a code SFN09.0219 in Taiwan was 72.7% in the past four years. These two cases cannot be identified as a hospital or community-acquired infection, however, a laboratory infection was suspected. The South Regional Center of TCDC and the local health bureau immediately conducted an on-site inspection at the laboratory, and recommended that the hospital biosafety committee should strengthen the biosafety education training of the personnel and regularly disinfect the equipment and environment to eliminate the possible risk of infections in the laboratory.