Occupational Safety and Prevention following a Workplace Tuberculosis Cluster, Central Taiwan, 2022

DOI: 10.6524/EB.2025010_41(19).0001

Yi-Hua Chung^*, Chiao-Wen Lin, Pei-Jiuan Chao, Shao-Hui Tsai, Ching-Fen Ko, Jhy-Wen Wu

2025 Vol.41 NO.19

Correspondence Author： Yi-Hua Chung^*

Abstract：

        From April to July 2022, two employees at a company in central Taiwan were diagnosed with tuberculosis. Mycobacterium tuberculosis isolates from both cases shared the same genotype, as confirmed by mycobacterial interspersed repetitive units analysis (MIRU). 
        The index case sought medical treatment as recommended by the company manager, presenting symptoms of weight loss and a persistent cough for months prior to the tuberculosis diagnosis. The second case had direct contact with the index case at the workplace. Although no tuberculosis lesions were found on chest X-ray during the initial contact examination, 8 weeks after terminating effective exposure, his interferon-gamma release assay (IGRA) was positive. Tuberculosis was diagnosed by chest X-ray and sputum culture. 
        Environmental investigation found poor ventilation at the workplace, which was located on the ground floor. We recommended the installation of industrial exhaust systems and a redesign of ventilation ducts connecting to rooftop exhaust equipment. We also recommended that the company establish a mechanism to track and manage employee health examinations. 
        After these interventions were implemented, by July 2023, this company reported no new cases of tuberculosis.