Study on the Relation Between Nasopharyngeal Carcinoma and EBV Antibody
1988 Vol.4 NO.2
In 1965, Old discovered high titer of EBV antibody in the serum of nasopharyngeal carcinoma patients. Since then, more EBV-related antigens such as VCA (viral capsid antigen), EA (early antigen). MA (membrance antigen), EBNA (EBV-induced nuclear antigen), and soluble antigen have been discovered！ Of them, EBV VCA antibody and EBV DNase antibody are related to the immunological reaction of nasopharyngeal carcinoma with high sensitivity and specificity2. Taiwan Area. ROC, is high in nasopharyngeal carcinoma. The relatively conservative estimate of the DOH cancer registration report in 1984 gave an annual incidence of 7.2 per 100,000 for male (the 5th cancer in male), and 3.3/100,000 for female (the 7th cancer in female). The study intends to investigate the relation between EBV and nasopharyngeal carcinoma by case-control matching method and analysis of serum antibody.