Imported Infection of Shigella sonnei Molecular Epidemiological Investigation of Cases of the Bali Tours
2004 Vol.20 NO.2
The 38 strains isolated from five members of the tour groups to the Bali Island collectively infected with bacillary dysentery on November 7 through 17, 2003, were confirmed Shigella sonnei. To understand the sources of infection, the present study selected two strains each from the Hsinchu and Yilan areas of the northern part of Taiwan known to have had outbreaks of Shigella sonnei infection confirmed by molecular typing, and eight strains of sporadic Shigella sonnei infection in the northern part of Taiwan in 2003 collected by the Kungyang Laboratory of the Center for Disease Control (the Laboratory) for analysis, to understand if the strains of the present incident were associated with the indigenous strains isolated in the northern part of Taiwan. The present study used the phenotype disk antimicrobial susceptibility test, and the genotype AP-PCR, plasmid profile analysis, and pulsed-field gel electrophoresis (PFGE) methods for the analysis of molecular epidemiological association.