The Epidemiology, Clinical Manifestations and Prognosis of Invasive Haemophilus Influenzae Type b Infection in Taiwan, 2000-2012

Su-Hsing Chen, En-Tzu Wang, Yen-Nan Chao, Ding-Ping Liu

2013 Vol.29 NO.19

Correspondence Author: Su-Hsing Chen

  • Division of Acute Infectious Diseases, Centers for Disease Control, Ministry of Health and Welfare, Taiwan


       During 2000 to 2012, a total of 272 confirmed cases of invasive Haemophilus influenzae type b infection (hereinafter referred to as Hib) were identified, of which male were 176 cases (64.7%) and female were 96 cases (35.3%), the male to female ratio was 1.83:1. Among the confirmed cases, children aged less than 5 years old were 159 cases (58.5%) which accounted for the largest number. The high season was winter (41.5%). The most common clinical manifestations were pneumonia (44%), followed by bacteremia (21%) and meningitis (16%); the patients with meningitis had the highest rate to develop sequelae.
       In recent years, the relevant vaccines have been introduced to Taiwan; the incidence of disease was significantly reduced. It has reduced to 0.01 cases per 100,000 population in 2012. Compared to developed countries in Europe and the United States, Taiwan is a low incidence country.