Report of First Guillain-Barré Syndrome Case Meeting the Brighton Collaboration Definition in Taiwan

Tsung-Pei Tsou1,2, Chang-Chiang Chen3, Tsam-Ming Kuo3, Wan-Ting Huang4

2010 Vol.26 NO.16

Correspondence Author： Tsung-Pei Tsou

Abstract：

Taiwan CDC has mobilized public health and medical resources in the preparedness and implementation of influenza A (H1N1) 2009 vaccination campaign, beginning November 1, 2009. During the campaign, close monitoring of adverse events following immunization is an essential part for ensuring vaccine safety. Neurological adverse events, in particular Guillain-Barré syndrome (GBS), have been one of the adverse events of specific interest because of the unique pathophysiological characteristics and historical experiences with influenza vaccines.
This report describes the first GBS case meeting the Brighton Collaboration definition in a patient who became sick after receiving the influenza A (H1N1) 2009 vaccine in Taiwan and discusses the application of case definition formulated by the Brighton Collaboration for monitoring GBS as an adverse event following immunization.