In collaboration with the RODS Laboratory at the University of Pittsburgh, Taiwan CDC has established its own “Real-time Outbreak and Disease Surveillance (RODS)” system since 2004 and renovated entirely in November 2006. By the use of automated transferred hospital emergency department ICD-9-coded diagnosis data, the RODS system, a syndromic surveillance system, shows its excellence in real-time monitoring seasonal enterovirus infection (EVI), influenza-like illness (ILI), acute hemorrhagic conjunctivitis and viral gastroenteritis epidemics. As of March 2009, there are more than 150 hospitals joining RODS, with the coverage rate of above 80% for nationwide daily emergency department visits.