During Week 19 (May 7th to 13th), 2017, one severe case of enterovirus infection was newly confirmed (Figure 1). A total of two enterovirus infection cases with severe complications (EVSC) has been confirmed by Taiwan CDC in 2017.One case was a boy aged below one year and the newly confirmed case was a five year old boy(Table 1). These two cases were caused by Coxsackie A2 and Coxsackie A6, respectively. Figure 2 shows the geographical distribution of these cases according to their residence.